HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenethylamine, (-)- → (3aR,6aS)-tert-butyl 5-(5-((S)-1-phenylethylcarbamoyl)pyridin-3-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenethylamine, (-)- | HCID 75818 | — |
| Reactant | 5-((3aR,6aS)-5-(tert-butoxycarbonyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)nicotinic Acid | HCID 67265367 | — |
| Product | (3aR,6aS)-tert-butyl 5-(5-((S)-1-phenylethylcarbamoyl)pyridin-3-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate | HCID 67266095 | — |
Reaction Steps
The product from Example 33B and (S)-1-phenylethanamine were processed as described in Example 33C to provide the title compound. MS (APCI) m/z 437 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148408B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-6fe38840c9614cb68fe2b66aa70f4127 |
| Source note | uspto-grants-2012_04 |