3,5-Dimethylaniline → HCID 67265711, compound

HRID 1685511Notes

Reaction equation

HRID 1685511 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:12][C@H:11]2[CH2:13][N:14]([C:16]3[CH:17]=[N:18][CH:19]=[C:20]([CH:24]=3)[C:21](O)=[O:22])[CH2:15][C@H:10]2[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:25][C:26]1[CH:27]=[C:28]([CH:30]=[C:31]([CH3:33])[CH:32]=1)[NH2:29]>>[CH3:25][C:26]1[CH:27]=[C:28]([NH:29][C:21]([C:20]2[CH:24]=[C:16]([N:14]3[CH2:15][C@@H:10]4[CH2:9][N:8]([C:6]([O:5][C:1]([CH3:4])([CH3:2])[CH3:3])=[O:7])[CH2:12][C@@H:11]4[CH2:13]3)[CH:17]=[N:18][CH:19]=2)=[O:22])[CH:30]=[C:31]([CH3:33])[CH:32]=1

Participants

3

Reactant 2

HCID 79493,5-DimethylanilineHCID 672653675-((3aR,6aS)-5-(tert-butoxycarbonyl)hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)nicotinic Acid

Product 1

HCID 67265711HCID 67265711, compound

Procedure

The product from Example 33B and 3,5-dimethylaniline were processed as described in Example 33C to provide the title compound. MS (APCI) m/z 337 (M+H)+.

Sources & evidence

ORD record
ord-6447f4983919442e95d507c41f4aa94b
Source dataset
uspto-grants-2012_04
Patent number
US08148408B2

Reaction notes

Loading…