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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1685530Generated: October 25, 2026

Cis-2-boc-hexahydropyrrolo[3,4-C]pyrrole → (3aR,6aS)-tert-butyl 5-(5-(benzyloxy)pyridin-3-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

https://huagongshe.com/reaction/1685530

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCis-2-boc-hexahydropyrrolo[3,4-C]pyrroleHCID 1514452—
Reactant3-(Benzyloxy)-5-bromopyridineHCID 15389198—
Product(3aR,6aS)-tert-butyl 5-(5-(benzyloxy)pyridin-3-yl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylateHCID 44190044—

Reaction Steps

3-(Benzyloxy)-5-bromopyridine and the product from Example 1C were processed as described in Example 53B to provide the title compound. MS (ESI) m/z 396 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148408B2
Source datasetuspto-grants-2012_04
ORD IDord-82ad05daf95744e29c7e9690f29f6620
Source noteuspto-grants-2012_04