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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1685586Generated: November 2, 2026

{2-[(1-Cyclopropylmethyl-6-trifluoromethyl-1H-indole-3-carbonyl)-amino]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester → {2-[(1-Cyclopropylmethyl-6-trifluoromethyl-1H-indole-3-carbonyl)-amino]-thiazol-5-ylsulfanyl}-acetic acid

https://huagongshe.com/reaction/1685586

Reaction equation

Participants

RoleNameHCIDCharge
Reactant{2-[(1-Cyclopropylmethyl-6-trifluoromethyl-1H-indole-3-carbonyl)-amino]-thiazol-5-ylsulfanyl}-acetic acid ethyl esterHCID 59514004—
Reactant{2-[(1-Cyclopropylmethyl-6-fluoro-1H-indole-3-carbonyl)-amino]-thiazol-4-ylsulfanyl}-acetic acidHCID 86610210—
Product{2-[(1-Cyclopropylmethyl-6-trifluoromethyl-1H-indole-3-carbonyl)-amino]-thiazol-5-ylsulfanyl}-acetic acidHCID 59513948—

Reaction Steps

{2-[(1-Cyclopropylmethyl-6-trifluoromethyl-1H-indole-3-carbonyl)-amino]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester was hydrolysed according to the procedure given in the procedure for the synthesis of {2-[(1-cyclopropylmethyl-6-fluoro-1H-indole-3-carbonyl)-amino]-thiazol-4-ylsulfanyl}-acetic acid

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148413B2
Source datasetuspto-grants-2012_04
ORD IDord-0721cfa1add7467e9ae2d4d8e6312430
Source noteuspto-grants-2012_04