2-Aminothiazole → 406728-86-7

Participants

Reaction Steps

1-(4-Fluorobenzyl)-pyrrole-2-carboxylic acid (1.18 g) was prepared from ethyl-pyrrole-2-carboxylate (1.39 g, 10.0 mmol) and 4-fluorobenzyl bromide (1.38 mL, 11.0 mmol) following the general procedures A and B. 1-(4-Fluorobenzyl)-pyrrole-2-carboxylic acid thiazol-2-ylamide (45 mg) was prepared from 1-(4-fluorobenzyl)-pyrrole-2-carboxylic acid (55 mg, 0.25 mmol) and 2-aminothiazole (25 mg, 0.25 mmol) following the general procedure F.

Provenance & Evidence