2-Aminothiazole → HCID 59513950, compound

Participants

Reaction Steps

2-(4-Fluorobenzyl)-5-propyl-2H-pyrazole-3-carboxylic acid (0.78 g) was prepared from 5-propyl-2H-pyrazole-3-carboxylic acid ethyl ester (0.91 g, 5.0 mmol) and 4-fluorobenzyl bromide (1.05 g, 5.5 mmol) following the general procedures D and E. 2-(4-Fluorobenzyl)-5-propyl-2H-pyrazole-3-carboxylic acid thiazol-2-ylamide (50 mg) was prepared from 2-(4-fluoro-benzyl)-5-propyl-2H-pyrazole-3-carboxylic acid (65 mg, 0.25 mmol) and 2-aminothiazole (25 mg, 0.25 mmol) following the general procedure F.

Provenance & Evidence