2-Aminothiazole → HCID 58217461, compound

Participants

Reaction Steps

1-(2-Methylallyl)-indazole-3-carboxylic acid (440 mg) was obtained from methyl indazole-3-carboxylate (0.5 g, 2.84 mmol) and 1-chloro-2-methylpropene (0.28 mL, 2.84 mmol, with a catalytic amount of sodium iodide) following the general procedures G and E. 1-(2-Methylallyl)indazole-3-carboxylic acid thiazol-2-ylamide (45 mg) was prepared from 1-(2-methylallyl)indazole-3-carboxylic acid (140 mg, 0.65 mmol) and 2-aminothiazole (65 mg, 0.65 mmol) following the general procedure H.

Provenance & Evidence