2-Methoxy-6-methylphenol → HCID 178492423, compound

HRID 1685702Notes

Reaction equation

HRID 1685702 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([CH3:9])[C:4]=1[OH:10].C(C1C=C(C=C(C)C=1O)[C:16]([NH:18][OH:19])=[NH:17])C>>[OH:10][C:4]1[C:5]([CH3:9])=[CH:6][C:7]([C:16]([NH:18][OH:19])=[NH:17])=[CH:8][C:3]=1[O:2][CH3:1]

Participants

3

Reactant 2

HCID 761732-Methoxy-6-methylphenolHCID 178436626HCID 178436626, compound

Product 1

HCID 178492423HCID 178492423, compound

Procedure

The title compound is prepared from commercially available 2-methoxy-6-methyl-phenol in analogy to literature procedures (e.g B. Roth et al. J. Med. Chem. 31 (1988) 122-129; and literature cited for 3-ethyl-4,N-dihydroxy-5-methyl-benzamidine); LC-MS: tR=0.50 min; [M+1]+=197.23.

Sources & evidence

ORD record
ord-f7b7b7744cde44a881eef64832e58267
Source dataset
uspto-grants-2012_04
Patent number
US08148410B2

Reaction notes

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