4-Cyanobenzenesulfonyl chloride → HCID 178453718, compound

Participants

Reaction Steps

The title compound is prepared in analogy to N-hydroxy-4-(2-hydroxy-ethylsulfamoyl)-benzamidine starting from 4-cyano-benzenesulfonyl chloride and (2-amino-ethyl)-carbamic acid tert-butyl ester; LC-MS: tR=0.40 min; [M+1]+=359.09; 1H NMR (D6-DMSO): δ1.35 (s, 9H), 2.73-2.81 (m, 2H), 2.92-3.00 (m, 2H), 5.96 (s, 2H), 6.78 (t br, J=5.5 Hz, 1H), 7.69 (t br, J=6.0 Hz, 1H), 7.75-7.79 (m, 2H), 7.86-7.90 (m, 2H), 9.92 (s, 1H).

Provenance & Evidence