HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Ethyl-5-formyl-thiophene-2-carboxylic acid → N-((S)-3-(2-Ethyl-4-[5-(4-ethyl-5-formyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-2-hydroxy-propyl)-2-hydroxy-acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Ethyl-5-formyl-thiophene-2-carboxylic acid | HCID 20067733 | — |
| Reactant | N-((S)-3-{2-Ethyl-4-[5-(5-formyl-3,4-dimethyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-2-hydroxy-propyl)-2-hydroxy-acetamide | HCID 86646446 | — |
| Product | N-((S)-3-(2-Ethyl-4-[5-(4-ethyl-5-formyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-2-hydroxy-propyl)-2-hydroxy-acetamide | HCID 86646451 | — |
Reaction Steps
The title compound is prepared according to Method E starting from 4-ethyl-5-formyl-thiophene-2-carboxylic acid and N—((S)-3-{2-ethyl-4-[5-(5-formyl-3,4-dimethyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-6-methyl-phenoxy}-2-hydroxy-propyl)-2-hydroxy-acetamide; LC-MS: tR=0.73 min; [M+1]+=474.20.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148410B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-9a21bdb23fe04d12a898988bed3416fb |
| Source note | uspto-grants-2012_04 |