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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1685750Generated: November 2, 2026

Dimethylamine → 4-[5-(5-Dimethylaminomethyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-2,6-dimethyl-phenol

https://huagongshe.com/reaction/1685750

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamineHCID 674—
Reactant5-[3-(4-Hydroxy-3,5-dimethyl-phenyl)-[1,2,4]oxadiazol-5-yl]-thiophene-2-carbaldehydeHCID 136377325—
Product4-[5-(5-Dimethylaminomethyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-2,6-dimethyl-phenolHCID 136355288—

Reaction Steps

The title compound is prepared from 5-[3-(4-hydroxy-3,5-dimethyl-phenyl)-[1,2,4]oxadiazol-5-yl]-thiophene-2-carbaldehyde and dimethylamine according to Method B; LC-MS: tR=0.75 min; [M+1]+=330.05.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148410B2
Source datasetuspto-grants-2012_04
ORD IDord-19f93626b9504d32b37196e1a64ed35b
Source noteuspto-grants-2012_04