Ethanolamine → HCID 67265471, compound

Participants

Reaction Steps

The title compound (6 mg) is prepared in analogy to Example 160 starting from methanesulfonic acid 2-{4-[5-(5-diethylaminomethyl-4-methyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-phenyl}-ethyl ester (50 mg, 111 μmol) and ethanolamine (34 mg, 556 μmol); LC-MS: tR=0.63 min; [M+1]+=415.07; 1H NMR (CDCl3): δ1.11 (t, J=7.0 Hz, 6H), 2.26 (s, 3H), 2.63 (q, J=7.0 Hz, 4H), 2.80-2.86 (m, 2H), 2.87-2.93 (m, 2H), 2.94-3.00 (m, 2H), 3.62-3.67 (m, 2H), 3.73 (s, 2H), 7.35 (d, J=8.0 Hz, 2H), 7.67 (s, 1H), 8.09 (d, J=8.0 Hz, 2H).

Provenance & Evidence