Methanesulfonyl chloride → HCID 67265929, compound

Participants

Reaction Steps

The title compound (3 mg) is prepared in analogy to Example 155 starting from 2-{4-[5-(5-diethylaminomethyl-4-methyl-thiophen-2-yl)-[1,2,4]oxadiazol-3-yl]-phenyl}-ethylamine (10 mg, 27 μmol) and methanesulfonyl chloride (4 mg, 35 μmol); LC-MS: tR=0.78 min; [M+1]+=448.99; 1H NMR (CDCl3): δ 1.11 (t, J=7.0 Hz, 6H), 2.26 (s, 3H), 2.64 (q, J=7.3 Hz, 4H), 2.89 (s, 3H), 2.96-3.01 (m, 2H), 3.49 (q, J=6.8 Hz, 2H), 3.73 (s, 2H), 4.23 (t br, J=6.3 Hz, 1H), 7.37 (d, J=8.0 Hz, 2H), 7.67 (s, 1H), 8.13 (d, J=8.3 Hz, 2H).

Provenance & Evidence