HCID 72529807, compound → HCID 59202217, compound

Participants

Reaction Steps

2-[4-(1,1-Dioxotetrahydro-1λ6-thiophen-2-ylidenemethyl)phenyl]propionic acid (90 mg) obtained in Example 41 was dissolved in methanol (2.0 ml), and to the solution was added 5% palladium/activated carbon (20 mg), and the mixture was stirred for 1 hour under hydrogen flow. The reaction mixture was filtered, and then the solvent was evaporated under reduced pressure. The residue was purified by column chromatography (hexane/ethyl acetate=1/2) to give the title compound (63 mg, 70%).

Provenance & Evidence