Dihydro-3(2H)-thiophenone → HCID 67265755, compound

HRID 1685825Notes

Reaction equation

HRID 1685825 reaction equation
[Br:1][C:2]1[C:3]([CH:16]=O)=[CH:4][C:5]([O:14][CH3:15])=[C:6]([CH:8]([CH3:13])[C:9]([O:11][CH3:12])=[O:10])[CH:7]=1.[O:18]=[C:19]1[CH2:23][CH2:22][S:21][CH2:20]1>>[Br:1][C:2]1[C:3]([CH:16]=[C:20]2[C:19](=[O:18])[CH2:23][CH2:22][S:21]2)=[CH:4][C:5]([O:14][CH3:15])=[C:6]([CH:8]([CH3:13])[C:9]([O:11][CH3:12])=[O:10])[CH:7]=1

Participants

3

Reactant 2

HCID 61252Dihydro-3(2H)-thiophenoneHCID 86639392HCID 86639392, compound

Product 1

HCID 67265755HCID 67265755, compoundYield 35%

Procedure

By using methyl 2-(5-bromo-4-formyl-2-methoxyphenyl)propionate (540 mg) obtained in Example 48 and 3-oxothiolane (370 mg), the title compound (230 mg, 35%) was obtained in the same manner as that of Example 1.

Sources & evidence

ORD record
ord-43662f7c2f2b4d65bd60fa40b059c100
Source dataset
uspto-grants-2012_04
Patent number
US08148421B2

Reaction notes

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