Dihydro-3(2H)-thiophenone → HCID 67265028, compound

HRID 1685827Notes

Reaction equation

HRID 1685827 reaction equation
[CH:1]([C:3]1[CH:8]=[CH:7][C:6]([CH:9]([CH3:14])[C:10]([O:12][CH3:13])=[O:11])=[CH:5][C:4]=1[N+:15]([O-:17])=[O:16])=O.[O:18]=[C:19]1[CH2:23][CH2:22][S:21][CH2:20]1>>[N+:15]([C:4]1[CH:5]=[C:6]([CH:9]([CH3:14])[C:10]([O:12][CH3:13])=[O:11])[CH:7]=[CH:8][C:3]=1[CH:1]=[C:20]1[C:19](=[O:18])[CH2:23][CH2:22][S:21]1)([O-:17])=[O:16]

Participants

3

Reactant 2

HCID 61252Dihydro-3(2H)-thiophenoneHCID 86639393HCID 86639393, compound

Product 1

HCID 67265028HCID 67265028, compoundYield 37%

Procedure

By using methyl 2-(4-formyl-3-nitrophenyl)propionate (360 mg) obtained in Example 54 and 3-oxothiolane (270 mg), the title compound (180 mg, 37%) was obtained in the same manner as that of Example 1.

Sources & evidence

ORD record
ord-4ae7109aad4c4ce08b6267cdbde4ffba
Source dataset
uspto-grants-2012_04
Patent number
US08148421B2

Reaction notes

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