Dihydro-3(2H)-thiophenone → HCID 67265826, compound

HRID 1685829Notes

Reaction equation

HRID 1685829 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:10]([CH3:15])[C:11]([O:13][CH3:14])=[O:12])[CH:5]=[CH:6][C:7]=1[CH:8]=O.[O:16]=[C:17]1[CH2:21][CH2:20][S:19][CH2:18]1>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:10]([CH3:15])[C:11]([O:13][CH3:14])=[O:12])[CH:5]=[CH:6][C:7]=1[CH:8]=[C:18]1[C:17](=[O:16])[CH2:21][CH2:20][S:19]1

Participants

3

Reactant 2

HCID 61252Dihydro-3(2H)-thiophenoneHCID 86639395HCID 86639395, compound

Product 1

HCID 67265826HCID 67265826, compoundYield 21.4%

Procedure

By using methyl 2-(3-chloro-4-formylphenyl)propionate (170 mg) obtained in Example 62 and 3-oxothiolane (115 mg), the title compound (50 mg, 21%) was obtained in the same manner as that of Example 1.

Sources & evidence

ORD record
ord-a6f32db43eb04be380f8e56e5f848ded
Source dataset
uspto-grants-2012_04
Patent number
US08148421B2

Reaction notes

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