1,4-Dioxane hydrochloride → N-(5-((1R,2S)-2-(3,5-Dimethoxybenzylamino)-1-hydroxypropyl)-2-hydroxyphenyl)methanesulfonamide

Participants

Reaction Steps

To the dioxane solution (1 mL) of the obtained amine (5) (47 mg, 0.11 mmol) was added 4N hydrochloric acid/dioxane solution (0.04 mL) and the resulting mixture was freeze-dried to obtain hydrochloric acid salt of the amine (5) as a white solid (27 mg, Yield: 55%).

Provenance & Evidence