4-Fluorobenzylamine → HCID 11708802, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 4-chloro-2,3-dimethyl-1H-pyrrolo[3,2-c]pyridine (1.16 g, 6.43 mmol) prepared in Preparation 1 and 4-fluorobenzylamine (3 ml, 26.2 mmol) was stirred for 12 hours at 160° C. The reaction mixture was cooled to room temperature and purified with silica gel column chromatography (ethyl acetate: 100%) to give the titled compound as a white solid. (Yield: 83.2%)

Provenance & Evidence