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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1686052Generated: November 2, 2026

Cyclopropanecarboxaldehyde → HCID 25017408, compound

https://huagongshe.com/reaction/1686052

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarboxaldehydeHCID 123114—
ReactantSodium borohydrideHCID 4311764—
ReactantAnlotinibHCID 25017411—
SolventEthanolHCID 702—
ProductHCID 25017408HCID 25017408—

Reaction Steps

The compound of Example 24 (100 mg) was refluxed with cyclopropanecarbaldehyde (2 eq) in EtOH (8 ml) for 4 hours. To the reaction was added NaBH4 (2.2 eq), the reaction was refluxed for 20 minutes and evaporated. The residue was purified with silica gel column to give the titled product (50 mg). Mass: (M+1), 462

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148532B2
Source datasetuspto-grants-2012_04
ORD IDord-075172a312df46d0b9831bcce6e784fd
Source noteuspto-grants-2012_04