Rhodanine → HCID 76609077, compound

HRID 1686148Notes

Reaction equation

HRID 1686148 reaction equation
[Br:1][C:2]1[CH:26]=[CH:25][CH:24]=[CH:23][C:3]=1[CH2:4][O:5][C:6]1[CH:13]=[C:12]([O:14][CH2:15][CH2:16][N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)[CH:11]=[CH:10][C:7]=1[CH:8]=O.[S:27]=[C:28]1[NH:32][C:31](=[O:33])[CH2:30][S:29]1>C1C=CC=CC=1>[Br:1][C:2]1[CH:26]=[CH:25][CH:24]=[CH:23][C:3]=1[CH2:4][O:5][C:6]1[CH:13]=[C:12]([O:14][CH2:15][CH2:16][N:17]2[CH2:22][CH2:21][O:20][CH2:19][CH2:18]2)[CH:11]=[CH:10][C:7]=1[CH:8]=[C:30]1[S:29][C:28](=[S:27])[NH:32][C:31]1=[O:33]

Participants

4

Reactant 2

HCID 1201546RhodanineHCID 86627412HCID 86627412, compound

Product 1

HCID 76609077HCID 76609077, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

2-(2-Bromobenzyloxy)-4-(2-morpholin-4-yl-ethoxy)benzaldehyde (43 mg, 0.102 mmol) obtained in step 4 was dissolved in benzene and reacted with 2-thioxothiazolidin-4-one in the same manner as in step 2 of Example 1 to afford the object compound (yellowish solid, 25 mg, 46%).

Workup

  1. customto afford the object compound (yellowish solid, 25 mg, 46%)

Sources & evidence

ORD record
ord-07c878fa3b4d4ebd8434bf53df93186c
Source dataset
uspto-grants-2012_04
Patent number
US08148541B2

Reaction notes

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