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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1686384Generated: November 2, 2026

2-Chloro-1-fluoro-4-methylsulfonylbenzene → 2-{4-Chloro-3-[2-chloro-4-(methylsulfonyl)phenoxy]phenyl}propanoic acid

https://huagongshe.com/reaction/1686384

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-1-fluoro-4-methylsulfonylbenzeneHCID 21340880—
ReactantMethyl 2-(4-chloro-3-hydroxyphenyl)propanoateHCID 67266160—
Product2-{4-Chloro-3-[2-chloro-4-(methylsulfonyl)phenoxy]phenyl}propanoic acidHCID 16124634—

Reaction Steps

The title compound was prepared by the method of example 2 step (iii) using the product of step (iii) and 3-chloro-4-fluorophenyl methyl sulfone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148572B2
Source datasetuspto-grants-2012_04
ORD IDord-8304a57557054ede908e66c562b4925f
Source noteuspto-grants-2012_04