4-Chloro-3-hydroxyphenylacetic acid → {4-Chloro-3-[4-(ethylsulfonyl)-2-fluorophenoxy]phenyl}acetic acid

HRID 1686389Notes

Reaction equation

HRID 1686389 reaction equation
[CH2:1]([S:3]([C:6]1[CH:11]=[CH:10][C:9](F)=[C:8]([F:13])[CH:7]=1)(=[O:5])=[O:4])[CH3:2].[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][C:22]([OH:24])=[O:23])=[CH:17][C:16]=1[OH:25]>>[Cl:14][C:15]1[CH:20]=[CH:19][C:18]([CH2:21][C:22]([OH:24])=[O:23])=[CH:17][C:16]=1[O:25][C:9]1[CH:10]=[CH:11][C:6]([S:3]([CH2:1][CH3:2])(=[O:5])=[O:4])=[CH:7][C:8]=1[F:13]

Participants

3

Reactant 2

HCID 30171834-Chloro-3-hydroxyphenylacetic acidHCID 265973661,2-Difluoro-4-ethylsulfonylbenzene

Product 1

HCID 16124638{4-Chloro-3-[4-(ethylsulfonyl)-2-fluorophenoxy]phenyl}acetic acid

Procedure

The title compound was prepared by the method of example 2 step (iii) using the product of step (ii) and the product of example 1 step (iii).

Sources & evidence

ORD record
ord-9d03e1c2e3524b069e3e7633d0e551d6
Source dataset
uspto-grants-2012_04
Patent number
US08148572B2

Reaction notes

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