4-Chloro-3-hydroxyphenylacetic acid → {4-Chloro-3-[2-cyano-4-(ethylsulfonyl)phenoxy]phenyl}acetic acid

HRID 1686393Notes

Reaction equation

HRID 1686393 reaction equation
Cl[C:2]1[CH:9]=[CH:8][C:7]([S:10]([CH2:13][CH3:14])(=[O:12])=[O:11])=[CH:6][C:3]=1[C:4]#[N:5].[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][C:23]([OH:25])=[O:24])=[CH:18][C:17]=1[OH:26]>>[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][C:23]([OH:25])=[O:24])=[CH:18][C:17]=1[O:26][C:2]1[CH:9]=[CH:8][C:7]([S:10]([CH2:13][CH3:14])(=[O:12])=[O:11])=[CH:6][C:3]=1[C:4]#[N:5]

Participants

3

Reactant 2

HCID 30171834-Chloro-3-hydroxyphenylacetic acidHCID 673903892-Chloro-5-(ethylsulfonyl)benzonitrile

Product 1

HCID 16122987{4-Chloro-3-[2-cyano-4-(ethylsulfonyl)phenoxy]phenyl}acetic acid

Procedure

The title compound was prepared by the method of example 2 step (iii) using the product of step (i) and the product of example 1 step (iii).

Sources & evidence

ORD record
ord-afb02892dfd24bcd87c5f36441677526
Source dataset
uspto-grants-2012_04
Patent number
US08148572B2

Reaction notes

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