2-Chloro-4-(ethylsulfonyl)-1-fluorobenzene → {3-Chloro-5-[2-chloro-4-(ethylsulfonyl)phenoxy]phenyl}acetic acid

HRID 1686400Notes

Reaction equation

HRID 1686400 reaction equation
[CH2:1]([S:3]([C:6]1[CH:11]=[CH:10][C:9](F)=[C:8]([Cl:13])[CH:7]=1)(=[O:5])=[O:4])[CH3:2].[Cl:14][C:15]1[CH:16]=[C:17]([CH2:22][C:23]([OH:25])=[O:24])[CH:18]=[C:19]([OH:21])[CH:20]=1>>[Cl:14][C:15]1[CH:16]=[C:17]([CH2:22][C:23]([OH:25])=[O:24])[CH:18]=[C:19]([O:21][C:9]2[CH:10]=[CH:11][C:6]([S:3]([CH2:1][CH3:2])(=[O:5])=[O:4])=[CH:7][C:8]=2[Cl:13])[CH:20]=1

Participants

3

Reactant 2

HCID 579047252-Chloro-4-(ethylsulfonyl)-1-fluorobenzeneHCID 596446192-(3-Chloro-5-hydroxyphenyl)acetic acid

Product 1

HCID 16123097{3-Chloro-5-[2-chloro-4-(ethylsulfonyl)phenoxy]phenyl}acetic acid

Procedure

The title compound was prepared by the method of example 2 step (iii) using the product of example 3 step (i) and the product of example 18 step (iv).

Sources & evidence

ORD record
ord-6014de9d3a9d4fecbaa9006f04c7e284
Source dataset
uspto-grants-2012_04
Patent number
US08148572B2

Reaction notes

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