2-Chloro-4-(ethylsulfonyl)-1-fluorobenzene → [3-[2-Chloro-4-(ethylsulfonyl)phenoxy]-5-(trifluoromethyl)phenyl]acetic acid

HRID 1686407Notes

Reaction equation

HRID 1686407 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.[CH2:16]([S:18]([C:21]1[CH:26]=[CH:25][C:24](F)=[C:23]([Cl:28])[CH:22]=1)(=[O:20])=[O:19])[CH3:17]>>[Cl:28][C:23]1[CH:22]=[C:21]([S:18]([CH2:16][CH3:17])(=[O:20])=[O:19])[CH:26]=[CH:25][C:24]=1[O:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:9])([F:10])[F:11])[CH:7]=1

Participants

3

Reactant 2

HCID 579047252-Chloro-4-(ethylsulfonyl)-1-fluorobenzeneHCID 690656243-Hydroxy-5-(trifluoromethyl)phenylacetic acid

Product 1

HCID 57791952[3-[2-Chloro-4-(ethylsulfonyl)phenoxy]-5-(trifluoromethyl)phenyl]acetic acid

Procedure

The title compound was prepared by the method of example 2 step (iii) using the product of example 25 step (iv) and the product of example 3 step (i).

Sources & evidence

ORD record
ord-3a0f38e747b64f6c9d57c72e52e41889
Source dataset
uspto-grants-2012_04
Patent number
US08148572B2

Reaction notes

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