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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1686408Generated: November 2, 2026

1,2-Difluoro-4-(methylsulfonyl)benzene → {3-Chloro-5-[2-fluoro-4-(methylsulfonyl)phenoxy]phenyl}acetic acid

https://huagongshe.com/reaction/1686408

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-Difluoro-4-(methylsulfonyl)benzeneHCID 2782743—
Reactant2-(3-Chloro-5-hydroxyphenyl)acetic acidHCID 59644619—
Product{3-Chloro-5-[2-fluoro-4-(methylsulfonyl)phenoxy]phenyl}acetic acidHCID 16123205—

Reaction Steps

The title compound was prepared by the method of example 2 step (iii) using 3,4-difluorophenyl methyl sulfone and the product of example 18 step (iv).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148572B2
Source datasetuspto-grants-2012_04
ORD IDord-67ae545a11364978bcfa840c2289d39d
Source noteuspto-grants-2012_04