{4-Chloro-3-[2-cyano-4-(ethylsulfonyl)phenoxy]phenyl}acetic acid → {3-Chloro-5-[2-cyano-4-(ethylsulfonyl)phenoxy]phenyl}acetic acid

HRID 1686409Notes

Reaction equation

HRID 1686409 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]([OH:11])=[O:10])=[CH:4][C:3]=1[O:12][C:13]1[CH:18]=[CH:17][C:16]([S:19]([CH2:22][CH3:23])(=[O:21])=[O:20])=[CH:15][C:14]=1[C:24]#[N:25].[Cl:26]C1C=C(CC(O)=O)C=C(O)C=1>>[Cl:26][C:7]1[CH:6]=[C:5]([CH2:8][C:9]([OH:11])=[O:10])[CH:4]=[C:3]([O:12][C:13]2[CH:18]=[CH:17][C:16]([S:19]([CH2:22][CH3:23])(=[O:21])=[O:20])=[CH:15][C:14]=2[C:24]#[N:25])[CH:2]=1

Participants

3

Reactant 2

HCID 16122987{4-Chloro-3-[2-cyano-4-(ethylsulfonyl)phenoxy]phenyl}acetic acidHCID 596446192-(3-Chloro-5-hydroxyphenyl)acetic acid

Product 1

HCID 16123206{3-Chloro-5-[2-cyano-4-(ethylsulfonyl)phenoxy]phenyl}acetic acid

Procedure

The title compound was prepared by the method of example 2 step (iii) using the product of example 12 step (ii) and the product of example 18 step (iv).

Sources & evidence

ORD record
ord-7814dbbb28b0453fa6033c34e7f6e659
Source dataset
uspto-grants-2012_04
Patent number
US08148572B2

Reaction notes

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