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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1686417Generated: October 26, 2026

1,2-Difluoro-4-ethylsulfonylbenzene → [3-[4-(Ethylsulfonyl)-2-fluorophenoxy]-5-(trifluoromethyl)phenyl]acetic acid

https://huagongshe.com/reaction/1686417

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-Difluoro-4-ethylsulfonylbenzeneHCID 26597366—
Reactant3-Hydroxy-5-(trifluoromethyl)phenylacetic acidHCID 69065624—
Product[3-[4-(Ethylsulfonyl)-2-fluorophenoxy]-5-(trifluoromethyl)phenyl]acetic acidHCID 57791938—

Reaction Steps

The title compound was prepared as described in example 2 step (iii) but instead using the product from example 25 step (iv) and the product from example 10 step (ii).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148572B2
Source datasetuspto-grants-2012_04
ORD IDord-518625887359462c8d3fd7a1ae399b9f
Source noteuspto-grants-2012_04