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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1686418Generated: October 25, 2026

2-Chloro-5-(ethylsulfonyl)benzonitrile → [3-[2-Cyano-4-(ethylsulfonyl)phenoxy]-5-(trifluoromethyl)phenyl]acetic acid

https://huagongshe.com/reaction/1686418

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-(ethylsulfonyl)benzonitrileHCID 67390389—
Reactant3-Hydroxy-5-(trifluoromethyl)phenylacetic acidHCID 69065624—
Product[3-[2-Cyano-4-(ethylsulfonyl)phenoxy]-5-(trifluoromethyl)phenyl]acetic acidHCID 16123318—

Reaction Steps

The title compound was prepared as described in example 2 step (iii) but instead using the product from example 25 step (iv) and the product from example 12 step (i).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148572B2
Source datasetuspto-grants-2012_04
ORD IDord-5b614919e27a463f83e3ac781e7fc9ec
Source noteuspto-grants-2012_04