2-Chloro-4-(ethylsulfonyl)-1-fluorobenzene → {3-Bromo-5-[2-chloro-4-(ethylsulfonyl)phenoxy]phenyl}acetic acid

HRID 1686435Notes

Reaction equation

HRID 1686435 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([OH:12])=[O:11])[CH:5]=[C:6]([OH:8])[CH:7]=1.[CH2:13]([S:15]([C:18]1[CH:23]=[CH:22][C:21](F)=[C:20]([Cl:25])[CH:19]=1)(=[O:17])=[O:16])[CH3:14]>>[Br:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([OH:12])=[O:11])[CH:5]=[C:6]([O:8][C:21]2[CH:22]=[CH:23][C:18]([S:15]([CH2:13][CH3:14])(=[O:17])=[O:16])=[CH:19][C:20]=2[Cl:25])[CH:7]=1

Participants

3

Reactant 2

HCID 579047252-Chloro-4-(ethylsulfonyl)-1-fluorobenzeneHCID 667341662-(3-Bromo-5-hydroxyphenyl)acetic acid

Product 1

HCID 57791934{3-Bromo-5-[2-chloro-4-(ethylsulfonyl)phenoxy]phenyl}acetic acid

Procedure

The title compound was prepared as described in example 2 step (iii) but instead using the product from step (v) and the product from example 3 step (i).

Sources & evidence

ORD record
ord-1893df8f72a542948c49bfc87ff9e937
Source dataset
uspto-grants-2012_04
Patent number
US08148572B2

Reaction notes

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