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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1686444Generated: November 1, 2026

3-Hydroxy-5-(trifluoromethyl)phenylacetic acid → [3-{[3-Methyl-5-(phenylsulfonyl)pyridin-2-yl]oxy}-5-(trifluoromethyl)phenyl]acetic acid

https://huagongshe.com/reaction/1686444

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Hydroxy-5-(trifluoromethyl)phenylacetic acidHCID 69065624—
Reactant2-Chloro-3-methyl-5-(phenylsulfonyl)pyridineHCID 86632976—
Product[3-{[3-Methyl-5-(phenylsulfonyl)pyridin-2-yl]oxy}-5-(trifluoromethyl)phenyl]acetic acidHCID 16123656—

Reaction Steps

The title compound was prepared as described in example 2 step (iii) but instead using the product from example 25 step (iv) and the product from step (ii).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148572B2
Source datasetuspto-grants-2012_04
ORD IDord-e8d2a4973d84407c927abfacc10b7587
Source noteuspto-grants-2012_04