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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1686446Generated: October 26, 2026

4-[(3-Chloro-4-fluorophenyl)sulfonyl]morpholine → [3-[2-Chloro-4-(morpholin-4-ylsulfonyl)phenoxy]-5-(trifluoromethyl)phenyl]acetic acid

https://huagongshe.com/reaction/1686446

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[(3-Chloro-4-fluorophenyl)sulfonyl]morpholineHCID 697826—
Reactant3-Hydroxy-5-(trifluoromethyl)phenylacetic acidHCID 69065624—
Product[3-[2-Chloro-4-(morpholin-4-ylsulfonyl)phenoxy]-5-(trifluoromethyl)phenyl]acetic acidHCID 16123657—

Reaction Steps

The title compound was prepared as described in example 2 step (iii) but instead using the product from example 25 step (iv) and the product from step (i).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148572B2
Source datasetuspto-grants-2012_04
ORD IDord-2a74c3d3267f4820b83a056edc848580
Source noteuspto-grants-2012_04