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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1686452Generated: October 25, 2026

2-(3-Chloro-5-hydroxyphenyl)acetic acid → {3-Chloro-5-[4-(ethylsulfonyl)-3-(trifluoromethyl)phenoxy]phenyl}acetic acid

https://huagongshe.com/reaction/1686452

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-Chloro-5-hydroxyphenyl)acetic acidHCID 59644619—
Reactant4-Bromo-1-(ethylsulfonyl)-2-(trifluoromethyl)benzeneHCID 68950753—
Product{3-Chloro-5-[4-(ethylsulfonyl)-3-(trifluoromethyl)phenoxy]phenyl}acetic acidHCID 16123768—

Reaction Steps

The title compound was prepared as described in example 2 step (iii) but instead using the product from example 18 step (iv) and the product from step (i).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148572B2
Source datasetuspto-grants-2012_04
ORD IDord-f03c9d2936504c9a9f09345dff74b8b9
Source noteuspto-grants-2012_04