(3-Chloro-5-mercaptophenyl)acetic acid → (3-Chloro-5-{[2-cyano-4-(ethylsulfonyl)phenyl]thio}phenyl)acetic acid

HRID 1686456Notes

Reaction equation

HRID 1686456 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([OH:12])=[O:11])[CH:5]=[C:6]([SH:8])[CH:7]=1.Cl[C:14]1[CH:21]=[CH:20][C:19]([S:22]([CH2:25][CH3:26])(=[O:24])=[O:23])=[CH:18][C:15]=1[C:16]#[N:17]>>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:9][C:10]([OH:12])=[O:11])[CH:5]=[C:6]([S:8][C:14]2[CH:21]=[CH:20][C:19]([S:22]([CH2:25][CH3:26])(=[O:24])=[O:23])=[CH:18][C:15]=2[C:16]#[N:17])[CH:7]=1

Participants

3

Reactant 2

HCID 66734548(3-Chloro-5-mercaptophenyl)acetic acidHCID 673903892-Chloro-5-(ethylsulfonyl)benzonitrile

Product 1

HCID 16123874(3-Chloro-5-{[2-cyano-4-(ethylsulfonyl)phenyl]thio}phenyl)acetic acid

Procedure

The title compound was prepared as described in example 2 step (iii) but instead using the product from step (i) and the product from example 12 step (i).

Sources & evidence

ORD record
ord-24d866fcc5144f1f8b9d7e13d584a3a6
Source dataset
uspto-grants-2012_04
Patent number
US08148572B2

Reaction notes

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