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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1686465Generated: October 26, 2026

2-Chloro-1-fluoro-4-[(4-fluorobenzyl)sulfonyl]benzene → [3-{2-Chloro-4-[(4-fluorobenzyl)sulfonyl]phenoxy}-5-(trifluoromethyl)phenyl]acetic acid

https://huagongshe.com/reaction/1686465

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-1-fluoro-4-[(4-fluorobenzyl)sulfonyl]benzeneHCID 68953429—
Reactant3-Hydroxy-5-(trifluoromethyl)phenylacetic acidHCID 69065624—
Product[3-{2-Chloro-4-[(4-fluorobenzyl)sulfonyl]phenoxy}-5-(trifluoromethyl)phenyl]acetic acidHCID 57791944—

Reaction Steps

The title compound was prepared as described in example 2 step (iii) but instead using the product from example 25 step (iv) and the product from example 34 step (i).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08148572B2
Source datasetuspto-grants-2012_04
ORD IDord-c6e908ff135e42d5a64d23a9dcf834d9
Source noteuspto-grants-2012_04