HCID 68950415, compound → HCID 16123985, compound

HRID 1686466Notes

Reaction equation

HRID 1686466 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.Cl[C:17]1[CH:24]=[CH:23][C:22]([S:25]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)(=[O:27])=[O:26])=[CH:21][C:18]=1[C:19]#[N:20]>>[C:19]([C:18]1[CH:21]=[C:22]([S:25]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)(=[O:26])=[O:27])[CH:23]=[CH:24][C:17]=1[O:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13]([OH:15])=[O:14])[CH:5]=[C:6]([C:8]([F:9])([F:10])[F:11])[CH:7]=1)#[N:20]

Participants

3

Reactant 2

HCID 68950415HCID 68950415, compoundHCID 690656243-Hydroxy-5-(trifluoromethyl)phenylacetic acid

Product 1

HCID 16123985HCID 16123985, compound

Procedure

The title compound was prepared as described in example 2 step (iii) but instead using the product from example 25 step (iv) and the product from example 44 step (i).

Sources & evidence

ORD record
ord-5886db19bf2b4a99af8438c45374a7aa
Source dataset
uspto-grants-2012_04
Patent number
US08148572B2

Reaction notes

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