HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Aminoindole → N2,N4-bis(indol-5-yl)-5-fluoro-2,4-pyrimidinediamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Aminoindole | HCID 78867 | — |
| Reactant | 2,4-Dichloro-5-fluoropyrimidine | HCID 250705 | — |
| Product | N2,N4-bis(indol-5-yl)-5-fluoro-2,4-pyrimidinediamine | HCID 22061088 | — |
Reaction Steps
In like manner to the preparation of N2,N4-bis(3-hydroxyphenyl)-5-fluoro-2,4-pyrimidinediamine, 2,4-dichloro-5-fluoropyrimidine and 5-aminoindole were reacted to yield N2,N4-bis(indol-5-yl)-5-fluoro-2,4-pyrimidinediamine. LCMS: ret. time: 20.26 min.; purity: 99%; MS (m/e): 359 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08148525B2 |
| Source dataset | uspto-grants-2012_04 |
| ORD ID | ord-7d7a37cdf0a241e7911b80c547d1fc4f |
| Source note | uspto-grants-2012_04 |