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HRID1688157

反应详情

EQUATION

反应方程式

HRID 1688157 的结构方程式

REACTANTS

反应物

1
结构：CCN1C(=O)OCCc2ccc(C(=O)OC(C)(C)C)cc21
HCID67264596

未命名化合物

PRODUCTS

生成物

1
结构：CCN1C(=O)OCCc2ccc(C(=O)O)cc21
HCID67264700

未命名化合物

收率 99.5%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl.O=C(O)C(F)(F)F
溶剂HCID21863450

未命名化合物

PROCEDURE

实验过程

A solution of 5-ethyl-6-oxo-5,6,8,9-tetrahydro-7-oxa-5-aza-benzocycloheptene-3-carboxylic acid tert-butyl ester (0.91 g, 3.12 mmol) was stirred in TFA/DCM (1:1, 3 mL) for 16 hours. The reaction was concentrated to provide 5-ethyl-6-oxo-5,6,8,9-tetrahydro-7-oxa-5-aza-benzocycloheptene-3-carboxylic acid (0.73 g).

WORKUP

后处理

  1. concentrationThe reaction was concentrated