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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 168823Generated: November 1, 2026

Hydrochloric Acid → 1-{2-[4-(5,11-Bis{[tert-butyl(dimethyl)silyl]oxy}-1,8-dihydro-2H-[1]benzopyrano[4,3-d][1]benzoxepin-8-yl)phenoxy]ethyl}piperidine

https://huagongshe.com/reaction/168823

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantTolueneHCID 1140—
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
Reactant1-[2-(4-Iodophenoxy)ethyl]piperidineHCID 15480655—
Reactant5,11-Bis{[tert-butyl(dimethyl)silyl]oxy}-1,8-dihydro-2H-[1]benzopyrano[4,3-d][1]benzoxepin-8-olHCID 21051984—
ReactantButyllithiumHCID 178418339—
Product1-{2-[4-(5,11-Bis{[tert-butyl(dimethyl)silyl]oxy}-1,8-dihydro-2H-[1]benzopyrano[4,3-d][1]benzoxepin-8-yl)phenoxy]ethyl}piperidineHCID 21051982—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-c1a89aee0b71468aa7ea0ef8b3a56785
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)