Carbon tetrabromide → HCID 66906229, compound

Participants

Reaction Steps

To a solution of (1-(2,6-dichlorophenyl)-4-isopropyl-1H-1,2,3-triazol-5-yl)methanol (3.0 g, 0.01048 mol) and CBr4 in CH2Cl2 (15 ml) is added a solution of triphenylphosphine (3.50 g, 0.01334 mol) in CH2Cl2 (10 ml) at 0° C. Stir the solution for 4 h at room temperature and concentrate in vacuo to give crude product. Purify by column chromatography over silica gel eluting with 7:3 hexane/ethyl acetate to give 3.0 g (82%) of the title compound. ES/MS m/e (79Br/81Br) 348/350 [M+H]+.

Provenance & Evidence