3-Bromo-4-methoxyphenylacetic acid → 2-(3-bromo-4-methoxyphenyl)ethanol

HRID 1689849Notes

Reaction equation

HRID 1689849 reaction equation
BrC1C=C(CCO)C=CC=1C.[Br:12][C:13]1[CH:14]=[C:15]([CH2:21][C:22](O)=[O:23])[CH:16]=[CH:17][C:18]=1[O:19][CH3:20].BrC1C=C(CC(O)=O)C=CC=1C>>[Br:12][C:13]1[CH:14]=[C:15]([CH2:21][CH2:22][OH:23])[CH:16]=[CH:17][C:18]=1[O:19][CH3:20]

Participants

4

Reactant 3

HCID 1366153-Bromo-4-methoxyphenylacetic acidHCID 178924312-(3-bromo-4-methylphenyl)acetic acidHCID 21091618HCID 21091618, compound

Product 1

HCID 230022542-(3-bromo-4-methoxyphenyl)ethanol

Procedure

By working as described for preparation 1b), but using compound 2a) from the previous step instead of compound 1a), the title compound is obtained.

Sources & evidence

ORD record
ord-04085d28839e47b29e13d9d1212629d5
Source dataset
uspto-grants-2012_04
Patent number
US08153637B2

Reaction notes

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