alpha-Bromo-o-fluorotoluene → HCID 59468959, compound

Participants

Reaction Steps

The title compound was prepared (80 mg) using a similar procedure as set out earlier in Description 11 starting from 1,1-dimethylethyl (2S,5R)-2-(aminocarbonyl)-5-(4-hydroxyphenyl)-2-methyl-1-pyrrolidinecarboxylate (D22, 55 mg, 0.17 mmol)) and 2-fluorobenzyl bromide; Rt (HPLC): 5.87 min; MS: (ES/+) 451 m/z: [M+Na+]; C24H29FN2O4 requires 428.

Provenance & Evidence