alpha-Bromo-o-fluorotoluene → HCID 59468919, compound

Participants

Reaction Steps

The title compounds were prepared (D52: 20 mg, 76%; D53: 3 mg, 11%) using a similar procedure to that set out earlier in Description 11 starting from 1,1-dimethylethyl (5S)-2-(4-hydroxyphenyl)-6-oxo-1,7-diazaspiro[4.5]decane-1-carboxylate (D51) and 2-fluorobenzyl bromide. D52: Rt (HPLC) 5.92 min; MS: (ES/+) 909 [dimerH+]. D53: Rt (HPLC) 5.73 min; MS: (ES/+) 909 [dimerH+].

Provenance & Evidence