Methyl 3-allyl-4-hydroxybenzoate → Methyl 4-hydroxy-3-propylbenzoate

Participants

Reaction Steps

To a mixed solution of methyl 4-hydroxy-3-(2-propen-1-yl)benzoate (12.16 g, 0.63 mol) and methanol (50 mL), 10% palladium carbon catalyst (608 mg) was added, and the mixture was stirred overnight under a hydrogen atmosphere. The catalyst was separated by filtration from the reaction solution which was then concentrated in vacuo. The obtained residue was purified using silica-gel column chromatography (hexane/ethyl acetate) and the title compound (10.83 g, yield 88%) was obtained as a colorless powder.

Provenance & Evidence