HRID1690150

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID3052153

未命名化合物

结构：C/C=C/c1cc(C(OCOC)(C(F)(F)F)C(F)(F)F)cnc1Oc1cccc(CO)c1

HCID59201010

未命名化合物

PRODUCTS

生成物

结构：C/C=C/c1cc(C(O)(C(F)(F)F)C(F)(F)F)cnc1Oc1cccc(CN2C(=O)NC(C)(c3ccc(OC(C)C)cc3)C2=O)c1

HCID44538128

未命名化合物

PROCEDURE

实验过程

After reacting and treating (E)-(3-(5-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-3-(prop-1-enyl)pyridin-2-yloxy)phenyl)methanol in a similar manner to Preparation example 3 b), 5-(4-(1-methylethoxy)phenyl)-5-methylimidazolidine-2,4-dione was used in place of 5-(benzo[d][1,3]dioxol-5-yl)-5-methylimidazolidine-2,4-dione in Example 1 for a similar reaction and treatment, and the title compound was obtained as a colorless oil.

WORKUP

后处理

customwas used in place of 5-(benzo[d][1,3]dioxol-5-yl)-5-methylimidazolidine-2,4-dione in Example 1 for a similar reaction and treatment

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-024bb22f8dbc4508be3d3642ce86f302
来源数据集: uspto-grants-2012_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08153634B2
来源说明: uspto-grants-2012_04

反应 SMILES

[F:1][C:2]([F:31])([F:30])[C:3]([C:12]1[CH:13]=[C:14](/[CH:27]=[CH:28]/[CH3:29])[C:15]([O:18][C:19]2[CH:20]=[C:21]([CH2:25]O)[CH:22]=[CH:23][CH:24]=2)=[N:16][CH:17]=1)([O:8]COC)[C:4]([F:7])([F:6])[F:5].[CH3:32][CH:33]([O:35][C:36]1[CH:41]=[CH:40][C:39]([C:42]2([CH3:49])[NH:46][C:45](=[O:47])[NH:44][C:43]2=[O:48])=[CH:38][CH:37]=1)[CH3:34]>>[F:31][C:2]([F:1])([F:30])[C:3]([C:12]1[CH:13]=[C:14](/[CH:27]=[CH:28]/[CH3:29])[C:15]([O:18][C:19]2[CH:20]=[C:21]([CH:22]=[CH:23][CH:24]=2)[CH2:25][N:44]2[C:43](=[O:48])[C:42]([C:39]3[CH:38]=[CH:37][C:36]([O:35][CH:33]([CH3:32])[CH3:34])=[CH:41][CH:40]=3)([CH3:49])[NH:46][C:45]2=[O:47])=[N:16][CH:17]=1)([OH:8])[C:4]([F:7])([F:6])[F:5]