HCID 86639436, compound → HCID 86639435, compound

Participants

Reaction Steps

1-(4-(4-(1,1,1,3,3,3-Hexafluoro-2-(methoxymethoxy)propan-2-yl)-2-propylphenoxy)-3-iodophenyl)ethanol (26 mg, 0.0446 mmol) was dissolved in dichloromethane (3 mL). The resultant mixture was added with manganese dioxide (78 mg, 0.891 mmol) at room temperature, and stirred at room temperature overnight. After completion of the reaction, the reaction solution was filtered using celite and concentrated in vacuum, and 1-(4-(4-(1,1,1,3,3,3-hexafluoro-2-(methoxymethoxy)propan-2-yl)-2-propylphenoxy)-3-iodophenyl) ethanone (16 mg, yield 60%) was obtained as a colorless oil.

Provenance & Evidence