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5-chloro-1-methyl-1H-indole-3-carbaldehyde → 5-chloro-1-methyl-3-(methylaminomethyl)-1H-indole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-chloro-1-methyl-1H-indole-3-carbaldehyde | HCID 16723796 | — |
| 反応物 | Methyl 2-((5-bromopyridin-2-yl)amino)acetate | HCID 22139049 | — |
| 生成物 | 5-chloro-1-methyl-3-(methylaminomethyl)-1H-indole | HCID 22139017 | 93% |
反応手順
According to the procedure of Preparation 13 (c), except substituting 5-chloro-1-methyl-1H-indole-3-carboxaldehyde for the, 3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (2.1 g, 93%) was obtained as an amber oil: MS (ES) m/e 209.0 (M+H)+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08153652B2 |
| 出典データセット | uspto-grants-2012_04 |
| ORD ID | ord-03e83df8ed4a43e6a7572f082de34ea9 |
| 出典メモ | uspto-grants-2012_04 |