3-Formyl-2-methylindole → HCID 22139069, compound

HRID 1690358Notes

Reaction equation

HRID 1690358 reaction equation
[CH3:1][C:2]1([CH3:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]([CH:11]=O)[CH2:3]1.C[C:15]1[NH:16]C2C(C=1C=O)=CC=CC=2>>[CH3:1][C:2]1([CH3:13])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]([CH2:11][NH:16][CH3:15])[CH2:3]1

Participants

3

Reactant 2

HCID 731663-Formyl-2-methylindoleHCID 221390871,1-dimethyl-3H-indene-3-carboxaldehyde

Product 1

HCID 22139069HCID 22139069, compoundYield 81%

Procedure

According to the procedure of Preparation 12, except substituting 1,1-dimethyl-3H-indene-3-carboxaldehyde for the 2-methylindole-3-carboxaldehyde, the title compound (3 g, 81%) was obtained as a reddish oil: MS (ES) m/e 188.2 (M+H)+.

Workup

  1. customAccording to the procedure of Preparation 12

Sources & evidence

ORD record
ord-08c3f304b4514d68b212815d1b1e5ec0
Source dataset
uspto-grants-2012_04
Patent number
US08153652B2

Reaction notes

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