Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1690373Generated: October 26, 2026

3-Formyl-2-methylindole → methyl 1-methyl-3-(methylaminomethyl)-1H-indole-7-carboxylate

https://huagongshe.com/reaction/1690373

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Formyl-2-methylindoleHCID 73166—
ReactantMethyl 3-formyl-1-methylindole-7-carboxylateHCID 22139012—
Productmethyl 1-methyl-3-(methylaminomethyl)-1H-indole-7-carboxylateHCID 2213914192%

Reaction Steps

According to the procedure of Preparation 12, except substituting 1-methyl-7-methoxycarbonyl-1H-indole 3-carboxaldehyde for the 2-methylindole-3-carboxaldehyde, the title compound (1.7 g, 92%) was obtained as an oil: MS (ES) m/e 233.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08153652B2
Source datasetuspto-grants-2012_04
ORD IDord-82fddf141653414d80bca03919fe831d
Source noteuspto-grants-2012_04